Anne-Marie Wills, M.D., M.P.H.


Physician Investigator (Cl)
Neurology, Research Institute
Assistant Professor of Neurology
Harvard Medical School
Assistant Neurologist
Neurology, Massachusetts General Hospital
MD Columbia University College of Physicians & Surgeons 2001
MPH Harvard T. H Chan School of Public Health 2009
adenosine a2 receptor antagonists; als; amyotrophic lateral sclerosis; antiparkinson agents; aryldialkylphosphatase; benzothiazoles; body mass index; caffeine; creatine; dyslipidemias; environmental risk factors; hallucinations; levodopa; neurodegenerative disease; organophosphates; parkinson's disease; phosphoric acid esters; tremor Dr. Wills' research focuses on environmental risk factors and determinants of neurodegenerative disease progression, including nutrition, caffeine and pesticides. Her multi-center clinical trial of nutrition in ALS (funded by the Muscular Dystrophy Association) showed that a calorically-dense diet was better tolerated and led to fewer adverse events, including deaths, than a standard diet (Wills et al. The Lancet, 2014).  This study was prompted by human and animal data which showed an increase in ALS survival from obesity and weight gain. She is also the M.G.H. Investigator on several Parkinson's Disease clinical trials testing therapeutic interventions in P.D.
Research website Publications Clinical Profile
awills@mgh.harvard.edu

Wang Ambulatory Care Cntr
15 Parkman Street
Boston, MA 02114