Amit V. Khera, M.D.


Physician Investigator (Cl)
Center for Genomic Medicine, Mass General Research Institute
Associate Director
Cardiovascular Disease Initiative, Broad Institute
Assistant Physician
Cardiology, Massachusetts General Hospital
Assistant Professor of Medicine
Harvard Medical School
MSc Harvard T.H. Chan School of Public Health 2017
MD University of Pennsylvania School of Medicine 2010
atherosclerosis; cardiovascular genetics; cardiovascular risk factors; computational biology; coronary artery disease; dna variation; genomic medicine; human genetics; lipid disorders; polygenic risk scores; preventative cardiology; weight

Amit V. Khera, MD MScis a cardiologist at Massachusetts General Hospital (MGH), Associate Director of the Precision Medicine Unit in the MGH Center for Genomic Medicine, and Associate Director of the Cardiovascular Disease Initiative at the Broad Institute of MIT and Harvard.

He received his MD with Alpha Omega Alpha distinction from the Perelman School of Medicine at the University of Pennsylvania, and went on to complete clinical training in Internal Medicine and cardiology at Brigham and Women's Hospital and MGH. He completed a Masters of Science from the Harvard School of Public Health, and a postdoctoral research fellowship with Dr. Sekar Kathiresan in human genetics at the Broad Institute of MIT and Harvard prior to accepting a faculty position.

He has developed substantial expertise in epidemiology, clinical medicine, and human genetics. Among his scientific contributions, he pioneered a new approach to quantify genetic risk for common diseases, developed biomarkers that provide new biologic insights, and analyzed large-scale gene sequencing data to highlight key pathways driving risk for cardiometabolic disease. His research program uses genetic variation as a tool to uncover new biology and enable enhanced clinical care informed by inherited susceptibility. In tandem with his research efforts he is co-leading a new Preventive Genomics Clinic at MGH to provide a clinical infrastructure for genome-first medicine.

Dr. Khera has authored more than 50 scientific publications, including lead-authored publications in the New England Journal of MedicineJournal of the American Medical AssociationCellNature Reviews GeneticsNature GeneticsJournal of the American College of Cardiology, and Circulation. He is a 2017 recipient of the National Lipid Association Junior Faculty Award and the 2019 recipient of the Douglas P. Zipes Distinguished Young Scientist Award from the American College of Cardiology.

Publications Clinical Profile
avkhera@mgh.harvard.edu
(617) 643-3388
Center for Genomic Medicine
Simches Building
185 Cambridge Street
6.256
Boston, MA 02114-2790