Hai Ning Shi, Ph.D., DVM
Mucosal Immunology and Biology Research Center, Mass General Research Institute
Associate Professor of Pediatrics
Harvard Medical School
|PhD McGill University 1996|
|DVM Qinghai Animal Science Veterinary Medicine College 1982|
Research in my lab is focused on three areas:
- The effects of chronic intestinal helminth infection on concurrent infection with bacterial enteropathogens
- The influence of early intestinal colonization with probiotic organisms on subsequent mucosal immune responses
- The effects of maternal gestational factors on the development of allergic disease in the offspring.
In each of these projects, we use a combination of in vitro and in vivo experiments to clarify the mechanisms that contribute to alterations in immune function.
The overall goal of these studies is to understand basic principles in immunoregulation in the gut and to use this information to shed light on diseases in which intestinal immunity is disturbed.