Maria Angela Franceschini, Ph.D.


Professor of Radiology
Harvard Medical School
Investigator
Athinoula A. Martinos Center for Biomedical Imaging, Mass General Research Institute
PhD University of Florence 1992
blood volume; brain; brain imaging; cerebrovascular circulation; diffuse correlation spectroscopy; evoked potentials somatosensory; fmri; hemodynamics; hemoglobins; near-infrared spectroscopy; neurophysiology; nirs; oxygen; oxygen consumption; somatosensory cortex; spectroscopy near-infrared; tomography optical

Maria Angela Franceschini, PhD, is widely recognized as a leader in the field of diffuse optical imaging in both neuroscience and clinical neuro-monitoring applications. Her research interests lie mainly in the development of novel optical imaging methods to achieve a deeper understanding of the brain and to impact the clinical management of patients, with a specific focus on investigating and quantifying oxygen delivery to and consumption by the brain in health and disease. Her activities are centered on non-invasive optical measurements in humans, from hardware and theoretical development to translational applications. Her research is intrinsically interdisciplinary and translational.

Dr. Franceschini’s broad vision and mission center on the translation of near-infrared spectroscopy (NIRS) imaging devices to general use as monitors of brain health and function. This can be achieved by pushing the development of more sophisticated, accurate and comprehensive devices, by refining the modeling of the measured signal to quantifiable biomarkers and by applying the novel tools in a wide range of applications with pilot, pivotal and clinical studies. She firmly believes in the impact that optical methods will have on advancing our understanding of how the brain works in health and disease. In particular, advanced NIRS tools have the potential to change patient management when used as bedside monitors, to provide a concrete measure of brain development in children in seconds by quantifying regional oxygen metabolism, and to assess adequacy of cerebral perfusion in astronauts in space by monitoring hypertension and intracranial pressure.

Optics @ Martinos Publications
mfranceschini@mgh.harvard.edu
6177264024
Athinoula A. Martinos Center for Biomedical Imaging
CNY-Building #149
149 13th Street
Charlestown, MA 02129