Investigator, Asst Prof (M) Anes Research Ichinose MGPO, Mass General Research Institute

Assistant Professor of Anaesthesia Harvard Medical School

drug discovery; hemoglobin; high throughput screening; oxygen; red blood cells; sickle cell disease; small molecules

Research Areas

• Development of high-throughput assays to assess hemoglobin gas-binding properties and red blood cell morphology
• Development of small molecules that modulate gas-binding of hemoglobin and red blood cells
• Development of small molecules for treating sickle cell disease
• Investigation of novel mechanisms by which small molecules inhibit red blood cell sickling

Research Description

I am a chemist with expertise in biochemistry and pharmaceutical sciences, focused on translating the biochemistry of heme-containing proteins and red blood cells into therapeutic strategies. My current research focus on developing high-throughput assays and small molecules for treating sickle cell disease.