Hiroaki Wakimoto, M.D., Ph.D.


Associate Investigator
Neurosurgery, Mass General Research Institute
Associate Professor of Neurosurgery
Harvard Medical School
Research Staff
Neurosurgery, Massachusetts General Hospital
MD Tokyo Medical And Dental University Hospital 1989
PhD Tokyo Medical and Dental University 1997
brain neoplasms; brain tumors; chemoresistance; genetic vectors; glioblastoma; gliomas; herpes simplex; malignant gliomas; neoplastic stem cells; oncolytic virotherapy; simplexvirus; viruses The ultimate goal of Dr. Wakimoto's research is to develop effective treatments for malignant brain cancer, glioblastoma. He has long been focusing on the use of oncolytic herpes simplex viruses as a tumor-killing agent as well as a gene delivery vehicle. His research interest includes exploration of the biology of "cancer stem cells" present in glioblastoma, which are speculated as the source of tumor recurrence.
Research website Publications
hwakimoto@mgh.harvard.edu
Brain Tumor Research Center
Simches Building
185 Cambridge Street
Boston, MA 02114-2790