Amy Barczak, M.D.


Physician Investigator (Cl)
Ragon Institute of MGH, MIT and Harvard, Research Institute
Assistant Professor of Medicine
Harvard Medical School
Assistant Physician
Medicine-Infectious Diseases, Massachusetts General Hospital
Associate Member
Broad Institute
MD Harvard medical school 2004
anti-bacterial agents; antigens bacterial; cellular models of infection; cyclic amp response element-binding protein; microbial sensitivity tests; mycobacterial; mycobacterium; mycobacterium smegmatis; mycobacterium tuberculosis; phagosomes; rna; tuberculosis; tuberculosis pulmonary; urine; virulence; virulence factors; virulence lipids

The Barczak laboratory is interested in understanding the TB host-pathogen interface as a means to developing novel therapeutic approaches to treating TB.

We currently have three areas of interest:

  1. Identifying and characterizing mycobacterial factors required for survival and virulence in cellular models of infection, with a particular focus on virulence lipids.
  2. Developing novel approaches to screening for compounds with anti-TB activity in the host.
  3. Using mycobacterial genetic tools to explore the host response to infection.
Research lab website Publications Clinical Profile
abarczak@mgh.harvard.edu

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