Physician Investigator (Cl) Surgical Oncology, Mass General Research Institute

Associate Professor of Surgery Harvard Medical School

Visiting Surgeon Surgical Oncology, Massachusetts General Hospital

Director, Melanoma Surgery Program Cancer Center, Massachusetts General Hospital

Surgical Director, Termeer Center for Targeted Therapies Cancer Center, Massachusetts General Hospital

Director, Therapeutic Intralesional Program Cancer Center, Massachusetts General Hospital

Emma and Bill Roberts MGH Research Scholar 2023-2028 Mass General Research Institute, Massachusetts General Hospital

MDPhD Thomas Jefferson University 2006

cancer epigenetics; cancer immunotherapy; cell proliferation; checkpoint blockade; circulating biomarkers of melanoma; ctdna; exosomes; high risk melanoma; high risk skin cancer; intralesional therapy; melanoma; neoadjuvant therapy; neural crest; next-gen sequencing; proteomics; skin cancer; tumor microenvironment

Dr. Boland's research focuses on questions relating to melanoma genetics, biology, and immunology using genomic, transcriptomic, and proteomic approaches to profiling patient-derived samples.

Current Research Interests:

1. Identification of circulating biomarkers of melanoma/cancer including circulating exosomes and/or ctDNA.
2. Analysis of treatment-related effects on the tumor and microenvironment, including changes occurring during treatment with immunotherapy.
3. Differential responses to immunotherapy and molecular/immunonological causes for heterogeneous responses to checkpoint blockade.
4. The combined use of surgery and systemic therapy for treatment of high risk melanoma patients.