Tian Lin, M.D., Ph.D.


Instructor in Investigation
Mucosal Immunology and Biology Research Center, Mass General Research Institute
Instructor in Pediatrics
Harvard Medical School
Research Staff
Pediatric Infectious Disease, Massachusetts General Hospital
MD Tongji Medical University 1994
PhD University of North Carolina Charlotte 2005
heme; hemoglobins; hemopexin; hmgb1 protein; inflammation; macrophage activation Dr. Lin has a longstanding interest in host-pathogen interactions in infectious diseases. Her PhD research focused on the host immune response to Salmonella infection. At the Warren Lab, Dr. Lin and her colleagues discovered the synergistic inflammation induced by heme and hemoglobin with multiple microbial TLR agonists and HMGB1, and has been studying hemopexin, a serum protein, as a potential therapeutic reagent to control overactive immune responses in several clinical conditions. These studies were published in many peer reviewed journals and are now the basis for multiple translational research endeavors. Dr. Lin is the principle investigator of the Shriners Hospital for Children grant “Hemopexin suppresses inflammation in burn wounds.” In addition to conducting laboratory research, Dr. Lin teaches preclinical courses at Harvard Medical School.
Warren Lab Publications
tlin7@mgh.harvard.edu

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