Lee Kaplan, M.D., Ph.D.


Physician Investigator (Cl)
Gastroenterology, Mass General Research Institute
Associate Professor of Medicine
Harvard Medical School
Associate Physician
Gastroenterology, Massachusetts General Hospital
MD Yeshiva University 1981
PhD Yeshiva University 1981
anti-obesity agents; bariatric surgery; energy balance; gastric bypass; metabolism; microbiome; obesity; obesity morbid; roux-en-y gastric bypass; weight loss Lee M. Kaplan, MD, PhD, graduated from Harvard University and received his medical degree and doctorate in molecular biology from the Albert Einstein College of Medicine at Yeshiva University. He completed an internship and residency in internal medicine and a fellowship in gastroenterology at Mass General and Harvard Medical School and a fellowship in genetics at Brigham and Women’s Hospital.

He is director of the fellowship program in Obesity Medicine and Nutrition at Mass General, director of the Blackburn Course in Obesity Medicine at Harvard Medical School and chairman emeritus of the Campaign to End Obesity. He currently serves as chair of the Obesity, Metabolism and Nutrition Section of the American Gastroenterological Association (AGA), chair of the Bariatric Surgery Section and chair of the Clinical Committee of the Obesity Society.

Dr. Kaplan’s research is focused on the physiological and molecular mechanisms of gastrointestinal regulation of energy balance and metabolic function, and his group has pioneered the development and use of rodent models for weight loss surgery and gastrointestinal devices to explore these mechanisms.  He is the author of more than 150 scientific and medical papers, including in The New England Journal of Medicine, Nature, Nature Genetics, Nature Medicine, Science Translational Medicine, the Proceedings of the National Academy of Sciences, the Journal of Clinical Investigation, Gastroenterology and the American Journal of Human Genetics.