Marcela Valderrama Maus, M.D., Ph.D.


Physician Investigator (Cl)
CCR Group C Monthly, Mass General Research Institute
Associate Professor of Medicine
Harvard Medical School
Assistant In Medicine
Medicine-Hematology/Oncology, Massachusetts General Hospital
Associate Member
Broad Institute
PhD University of Pennsylvania School of Medicine 2003
MD University of Pennsylvania School of Medicine 2005
antigens; cancer immunotherapy; cellular immunology; chimerism; genetic engineering; immunotherapies; t cells Using the immune system as a cancer treatment has the potential to induce long-term, durable remissions, and perhaps even cures for some patients. The T cells of the immune system are able to specifically kill the target cells they recognize. T cells are also able to persist in the body for many years, and form immune ‘memory,’ which enables the possibility of long-term protection. The Maus laboratory is interested in using genetic engineering techniques to re-direct T cells to find and kill tumor cells while sparing healthy tissues. We aim to: develop new ways to design molecular receptors to target T cells to liquid and solid tumors; use T cells as delivery vehicles for other drugs, and use drugs to help T cells work against tumors; and understand how T cells can work as “living drugs” to treat patients with cancer.
Maus Lab Publications Clinical Profile
mvmaus@mgh.harvard.edu
6177265619

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