Chen Institute MGH Research Scholar 2024-2029 Mass General Research Institute, Massachusetts General Hospital

Clinicn Investigator, Assc Prf Endocrine Division, Mass General Research Institute

Associate Professor of Medicine Harvard Medical School

Associate Physician Medicine-Endocrine, Massachusetts General Hospital

Associate Member Broad Institute

M.D., Ph.D. Harvard Medical School 2009

PhD Harvard Medical School, Office of the Registrar 2009

M.D.; Ph.D. Harvard Medical School 2009

bone resorption; hyperparathyroidism; osteoblasts; osteoclasts; osteogenesis; osteogenesis imperfecta; osteoporosis; osteoporotic fractures The Wein laboratory studies molecular mechanisms controlling bone cell differentiation and function. Our research focuses on osteocytes, the most abundant and least understood cell type in bone. We study mechanisms of osteocyte mechano-transduction, dendrite development, and responses to parathyroid hormone. Ultimately, we aim to develop new osteoporosis therapies based on a detailed understanding of bone cell biology.