Physician Investigator (Cl) Cancer Center, Mass General Research Institute

Professor of Medicine Harvard Medical School

Physician Medicine-Hematology/Oncology, Massachusetts General Hospital

MD Harvard Medical School 1988

acute; alkylating agents; hematopoietic stem cells; leukemia myeloid; myelodysplastic syndromes; myeloid leukemia; myeloid malignancies; oncogene proteins fusion; somatic mutations

The Graubert laboratory focuses on the molecular basis of human blood cancers, including acute myeloid leukemia and myelodysplastic syndromes.  The laboratory utilizes a variety of genomic platforms to interrogate primary samples from patients with myeloid malignancies to identify inherited and somatic mutations that drive these diseases.  The goal of these studies is to gain insight into the biological basis of myeloid leukemias, and to improve strategies for diagnosis, risk stratification, and targeted therapy.