Physician Investigator (Cl) Cardiovascular Research Center, Mass General Research Institute

Assistant Professor of Medicine Harvard Medical School

Temporary Academic Medicine, Harvard Medical School

Assistant In Medicine Cardiology, Massachusetts General Hospital

MD University of Chicago, Pritzker School of Medicine 2010

cardiac disease risk; cardiometabolic disease; cardiovascular imaging; early markers of cardiometabolic disease risk; positron emission tomography; psychosocial and environmental stressors; stress and cardiovascular disease

Cardiometabolic disease has emerged as a growing public health problem across the world. While a large proportion of cardiometabolic disease risk arises from heritable factors and health behaviors, it has hypothesized for years that psychosocial and environmental stressors contribute to the development of these pathologies.

Nevertheless, the mechanisms are incompletely defined. Dr. Osborne's research implements advanced cardiovascular imaging, specifically positron emission tomography, to: 1) understand the mechanisms that link psychosocial and environmental stressors to cardiometabolic diseases, 2) identify early markers of cardiometabolic risk, and 3) evaluate the effect of interventions on imaging biomarkers of cardiometabolic diseases.