John M Dubach, Ph.D.


Assistant Investigator
Athinoula A. Martinos Center for Biomedical Imaging, Mass General Research Institute
Assistant Professor of Radiology
Harvard Medical School
Research Staff
Radiology, Massachusetts General Hospital
PhD Northeastern University 2012
biosensing techniques; hyponatremia; nanotechnology; sodium; sodium compounds

The Lab has a unique operation. We have always focused on selecting ideas that would have the greatest positive impact for humanity (for some current projects see here). Our primary focus is to:

  • Obtain a deeper understanding of human biology in health and disease
  • Translate new biological understanding into clinically useful diagnostics
  • Identify new therapeutic approaches and drug targets
The lab uses a variety of tools and platforms (bioimaging, chemical biology, bioengineering) for data acquisition. In general, we aim at obtaining:
  • Quantitative in vivo measurements
  • Systems-wide global measurements
  • Dynamic, serial measurements
  • An fine-grained understanding of in vivo function
We strongly encourage an unusual interdisciplinary approach, fostering collaboration between scientists and clinicians from diverse backgrounds. This convergence approach has led to many exciting discoveries and innovations at the Weissleder Lab.