Aaron Aguirre, M.D., Ph.D.


Principal Investigator
Wellman Center for Photomedicine, Massachusetts General Hospital
Principal Investigator
Center for Systems Biology, Massachusetts General Hospital
Clinicn Investigator, Asst Prf
HVI CV MGH Critical Care PO, Mass General Research Institute
Assistant Professor of Medicine
Harvard Medical School
Associate Physician
Medicine-Cardiovascular Medicine, Massachusetts General Hospital
MD Harvard Medical School/ BWH 2008
PhD Massachusetts Institute of Technology 2008
advanced cardiac life support; artificial intelligence; cardiac arrest; cardiovascular imaging; catheter imaging; digital health; heart failure; heart function tests; high-resolution optical imaging; intravital multiphoton microscopy; machine learning; mechanical circulatory support systems; medical devices; myocardial infarction; shock


Aaron Aguirre, M.D., PhD is an attending cardiologist and critical care physician at the Massachusetts General Brigham and an Assistant Professor of Medicine at Harvard Medical School.

He received his medical degree from Harvard Medical School and his doctoral degree in electrical and biomedical engineering from the Massachusetts Institute of Technology. He trained in internal medicine, cardiology, and critical care at the Brigham and Women's Hospital. 

Dr. Aguirre's laboratory is part of the Wellman Center for Photomedicine and the Center for Systems Biology at Massachusetts General Hospital (MGH), and is closely affiliated with the MGH Cardiovascular Research Center. The lab develops and applies advanced imaging and microscopy technologies to investigate the pathophysiology of myocardial infarction, heart failure, and circulatory shock. The lab has pioneered the use of cardiac intravital microscopy to study the beating heart at cellular resolution in animal models and has explored multiple applications of this technology. 

In addition, Dr. Aguirre's lab develops signal processing and artificial intelligence methods and medical device technologies to improve the care of patients in the intensive care unit. The lab has a particular interest in studying the conditions of acute decompensated heart failure, circulatory shock, and cardiac arrest. The team collaborates closely with the Biomedical Engineering department at Mass General Brigham in this effort. 

Dr. Aguirre is also a clinical affiliate of the MGH Healthcare Transformation Lab, where he leads projects involving the development of new digital health tools for use in the intensive care unit.

As a critical care cardiologist in the 
MGH Heart Center Intensive Care Unit, his clinical practice involves care of medical and surgical patients with all forms of advanced heart disease. He has particular interest in the area of acute decompensated heart failure and the use of mechanical circulatory support devices.