Physician Investigator (Cl) Cardiovascular Research Center, Mass General Research Institute

Associate Professor of Medicine Harvard Medical School

Assistant Physician Cardiology, Massachusetts General Hospital

MD 2000

atrial fibrillation; balloon occlusion; cardiac resynchronization therapy; cytological techniques; defibrillators, implantable; eisenmenger complex; heart failure, systolic; kcnq1 potassium channel; myocytes, cardiac; tachycardia, atrioventricular nodal reentry; ventricular remodeling

My research focuses on discovering new types of blood markers that can help predict patients who develop worsening heart failure or arrhythmias. My laboratory has optimized new methods to visualize and study vesicles in the blood that can carry some of the markers and transfer them between different organs as a new type of signaling.

We use the discovery of these new types of blood markers to study their functional role in mediating heart disease progression and are trying to develop new types of therapies to halt the progression of heart failure and arrhythmias.