Jenna Galloway, Ph.D.
Center for Regenerative Medicine, Mass General Research Institute
Associate Professor of Orthopedic Surgery
Harvard Medical School
Harvard Stem Cell Institute
Orthopaedic Surgery, Massachusetts General Hospital
|PhD Harvard University 2006|
One major area of research in the laboratory aims to identify the cues that direct progenitor cells to become mature tendons and ligaments. During embryogenesis, progenitor cell populations will form the tendon or cartilage tissues in our limbs, head and spine. We are interested in elucidating the factors that regulate this fate decision, expand tendon and ligament populations and promote more faithful differentiation into these lineages.
We are also focused on understanding the critical factors that coordinate the attachments between muscle, tendon, and bone. By combining live-imaging and high-throughput screening approaches, our goal is to identify the molecules and cellular behaviors governing these processes. In the long term, my laboratory aims to transform these discoveries into regenerative biology solutions to better heal and repair tendon and ligament injuries.
Current Research Projects:
- Tendon progenitor cell regulation
- Myo-tendinous and osteo-tendinous junctions
- Directed differentiation into tendon and ligament tissues