Matthew Rosen, Ph.D.

Associate Professor of Radiology
Harvard Medical School
Associate Investigator
Athinoula A. Martinos Center for Biomedical Imaging, Mass General Research Institute
Kiyomi and Ed Baird MGH Research Scholar 2022-2027
Mass General Research Institute, Massachusetts General Hospital
PhD University of Michigan 2001
automap; dissolution dnp; free radical imaging; hyperpolarized imaging; lfi; low magnetic field mri; magnetic resonance imaging; mri; nanodiamonds; sabre; superconducting mri scanners; traumatic brain injury

Dr. Matt Rosen is a physicist, tool-builder, and inventor whose research bridges the spectrum from fundamental physics to applied bioimaging work in the field of MRI. He established the Low-Field MRI and Hyperpolarized Media Laboratory at the Athinoula A. Martinos Center for Biomedical Imaging to focus on the continued development of new hyperpolarization methods and MRI-based tools.

The Rosen Lab focuses on new methods and tools to enable unconventional approaches to MRI scanner construction. This includes the development of new acquisition strategies for robust ultra-low magnetic field implementations of MRI focused on brain imaging. The laboratory also explores opportunities provided by hyperpolarization including in vivo Overhauser DNP, SABRE, and spin-exchange optical pumping.

We create new quantitative strategies for the acquisition and the reconstruction of highly-undersampled imaging data including neural network deep learning based approaches such as AUTOMAP that leverage low-cost scalable-compute. Matt co-directs the Center for Machine Learning at Martinos.