Associate Professor of Radiology Harvard Medical School

Investigator, Assoc Prof (M) Radiology, Mass General Research Institute

Kiyomi and Ed Baird MGH Research Scholar 2022-2027 Mass General Research Institute, Massachusetts General Hospital

automap; dissolution dnp; free radical imaging; hyperpolarized imaging; lfi; low magnetic field mri; magnetic resonance imaging; mri; nanodiamonds; sabre; superconducting mri scanners; traumatic brain injury

Dr. Matt Rosen is a physicist, tool-builder, and inventor whose research bridges the spectrum from fundamental physics to applied bioimaging work in the field of MRI. He established the Low-Field MRI and Hyperpolarized Media Laboratory at the Athinoula A. Martinos Center for Biomedical Imaging to focus on the continued development of new hyperpolarization methods and MRI-based tools.

The Rosen Lab focuses on new methods and tools to enable unconventional approaches to MRI scanner construction. This includes the development of new acquisition strategies for robust ultra-low magnetic field implementations of MRI focused on brain imaging. The laboratory also explores opportunities provided by hyperpolarization including in vivo Overhauser DNP, SABRE, and spin-exchange optical pumping.

We create new quantitative strategies for the acquisition and the reconstruction of highly-undersampled imaging data including neural network deep learning based approaches such as AUTOMAP that leverage low-cost scalable-compute. Matt co-directs the Center for Machine Learning at Martinos.