Thomas Lee Collier, Ph.D.

Associate Investigator
Gordon Center for Medical Imaging, Mass General Research Institute
Research Staff
Radiology, Massachusetts General Hospital
PhD Carleton University 1989
binding, competitive; positron-emission tomography; radiopharmaceuticals; receptors, sigma; tomography, emission-computed

NNMI encompasses Clinical Service, Education and Research and the MGH PET Core. The research areas are organized into three Centers of excellence: PET Radiochemistry Discovery (CPRD); Advanced Radiological Sciences (CARS); and Translational Nuclear Medicine and Molecular Imaging (CTNMI).

The three pillars of MGH NMMI are Clinical, Education and Research. The clinical operation provides full service nuclear medicine imaging (single photon and PET agents) using SPECT, PET, PET-CT and PET-MR and therapy services. The Educational program includes a nuclear radiology fellowship and comprehensive graduate student and post doctoral education including an NIH T32 and graduate courses at MIT. NMMI research encompasses three broad overlapping areas: 1) radiochemistry discovery; 2) imaging science and instrumentation; and 3) preclinical and clinical research. From 2008 to 2012, NMMI has experienced explosive growth in research personnel 25 to 110, research space (~3,000 sq. ft. to ~13,000 sq. ft.) and external funding (~$1M to ~$12M per year).

NMMI research includes single photon, PET and optical imaging. These areas explore agent discovery, validation and translational studies. As multimodal imaging is critical for molecular imaging, NMMI have research efforts in CT, MR and ultrasound. The research has evolved into three Centers, which constructively overlap. These efforts are located in research laboratories (~13,000 sq ft) in the MGH main campus and at the research campus in Charlestown.