Christine A Vaine, Ph.D.

Instructor in Investigation
Neurology, Mass General Research Institute
Instructor in Neurology
Harvard Medical School
Research Staff
Neurology, Massachusetts General Hospital
PhD University of Massachusetts Medical School 2010
alternative splicing; biomarker studies; dystonia; dystonia cell culture models; flow cytometry; glial cells; high-throughput screening assays; microglia; neurodegeneration; neurodegenerative diseases; neuroinflammation Christine graduated from the University of Massachusetts, Amherst in 2005 with a B.S. in microbiology. She received her Ph.D. in immunology in 2010 from Dr. Robert Finberg’s laboratory at the University of Massachusetts Medical School in Worcester. Her graduate work focused on imaging antibody-mediated endocytosis pathways as well as characterizing particle-induced innate immune responses. She joined Dr. Roy Soberman’s laboratory as a post-doctoral research fellow in 2010 to study the role of the inhibitory receptor CD200R1 in regulating immune cell activation and signaling. In 2014, she joined Dr. Cristopher Bragg's laboratory as an instructor to investigate the genetic basis for disease in X-linked Dystonia Parkinsonism (XDP). She is currently working to identify differentially regulated pathways in patient iPSC-derived cells lines and developing a screening assay for transcript modulation in XDP lines in collaboration with industry partners.
Collaborative Center for XDP Publications
CNY-Building #149
149 13th Street
Rm 6214
Charlestown, MA 02129