Investigator, Assoc Prof (M) Pulmonary, Mass General Research Institute

Associate Professor of Medicine Harvard Medical School

asthma; bronchoscopy; coronary vessels; esophagoscopy; esophagus; fiber optic technology; image enhancement; imaging three-dimensional; lung cancer; lung diseases; lung imaging; microscopy; optical frequency domain imaging; optics and photonics; pulmonary medicine; smoke inhalation injury; therapeutic irrigation; tomography optical coherence Optical imaging technologies have many attractive properties that make them ideal for investigating the lung including that they are non-destructive, are amenable to implementation using flexible small diameter fiber-optic catheters, do not require a transducing medium, and in many cases rely on endogenous contrast. Of particular interest to our laboratory is the development, use and clinical translation of optical imaging systems and techniques, particularly optical frequency domain imaging (OFDI), to address challenges in pulmonary medicine. OFDI is a second-generation optical coherence tomography imaging technology that can be used to conduct volumetric microscopy in vivo. We are currently investigating the use of OFDI for studying lung cancer, asthma, and smoke inhalation injury in ex vivo, preclinical and clinical studies.