Sachin J Shah, MD, MPH

I am a physician investigator in the Division of General Internal Medicine and the Center for Aging and Serious Illness at MGH. My research program aims to help older adults make individualized treatment decisions when they face high-stakes medical decisions, like deciding to use blood thinners or undergo a procedure. After completing my training in Internal Medicine and a General Medicine Research Fellowship at Massachusetts General Hospital, I joined the faculty at UCSF. After five years at UCSF, I returned to Massachusetts General Hospital, where I provide clinical care, supervise trainees, and conduct research.

My research program uses epidemiologic methods and core aging concepts to better define the risks and benefits of high-risk therapeutics. High-stakes clinical decisions are those with both substantial benefit and harm. My work focuses on (1) the generalizability of clinical trials to older adults and (2) individualizing estimates of benefit and harm for older adults. I also devote substantial attention to defining and measuring vulnerability in older adults. My work has focused on social vulnerability by defining the interaction between social resources and medical illness. My work is funded by the National Institute on Aging and supported by the Department of Medicine at MGH.

I am very proud of my work as a mentor. In addition to my research program, I serve as the General Medicine Fellowship Director at MGH.