Ryan B Corcoran, M.D., Ph.D.
Cancer Center, Massachusetts General Hospital
Associate Professor of Medicine
Harvard Medical School
Hematology-Oncology, Massachusetts General Hospital
|MD Stanford University School of Medicine 2006|
|PhD Stanford University School of Medicine 2006|
Since cancer cells often become resistant to these targeted therapies by activating alternative signaling pathways, we focus on identifying these key resistance signals in cancer cells. We utilize this information to devise effective combinations of targeted therapies that anticipate and ultimately overcome these mechanisms of drug resistance. Overall, our goal is to develop promising therapeutic strategies that can be evaluated in clinical trials for patients whose cancers are driven by speciﬁc mutations.