Priscilla Brastianos, M.D.


Physician Investigator (Cl)
Cancer Center, Mass General Research Institute
Associate Professor of Medicine
Harvard Medical School
Assistant Physician
Hematology-Oncology, Massachusetts General Hospital
Associate Member
Broad Institute
MD Johns Hopkins University School of Medicine 2006
angiogenesis inhibitors; brain neoplasms; craniopharyngioma; meningeal carcinomatosis; poetry as topic; sacrum; vascular endothelial growth factors

The Brastianos laboratory studies genomic drivers of human brain tumors. A lack of understanding of the molecular drivers of many brain tumors has hampered the development of novel therapies for many brain cancers. Our overarching objective is to characterize molecular drivers of both primary brain tumors and brain metastases, and accelerate the development of novel therapeutic approaches for these diseases.

We recently discovered clinically significant genetic drivers in meningiomas, craniopharyngiomas, hemangioblastomas, glioneuronal tumors and brain metastases. We are currently investigating the role of these genomic drivers as potential therapeutic targets. Additionally, we are expanding our investigations to further elucidate the molecular evolution of the metastatic process to the central nervous system.

Research lab website Publications Clinical Profile
pbrastianos@mgh.harvard.edu

Yawkey Center Outpatient Care
32 Fruit Street
Boston, MA 02114