Clinical Trials Director-McCance Center for Brain Health Neurology, Massachusetts General Hospital

Instructor in Investigation Neurology, Mass General Research Institute

Instructor in Neurology Harvard Medical School

alzheimer disease; amino acids; biomarker discovery; blood-brain barrier; cerebral bioenergetics; clinical trials; cognition; cystic fibrosis; diet; fatty acids; genetics; micronutrients; minerals; molecular epidemiology; mri; nutrient biomarkers; nutritional metabolism; precision medicine; vascular dementia; vitamins; white matter Exploring the role of diet and nutritional metabolism in the promotion of brain health and prevention of cognitive decline and dementia; Nutrient transport systems and the blood-brain barrier; Fatty acid metabolism and white matter lesions and intergrity; clinical and translational research; clinical trial design, particularly phase 2 biomarker-based trials using neuroimaging, blood and CSF biomarkers of disease and nutritional intake and metabolism; establishing distinct nutritional requirements for cognitive health and prevention of neurodegenerative and cerebrovascular disorders based on the holistic integration of nutritional neuroscience, genetics and precision medicine.