Mark Garret, MD


Physician Investigator (Cl)
Neurological Clinical Research Institute, Mass General Research Institute
Instructor in Neurology
Harvard Medical School
Assistant In Neurology
Massachusetts General Hospital
Assistant In Neurology
Massachusetts General Hospital
B.S. Stanford University 2011
MD Perelman School of Medicine at the Univeristy of Pennsylvania 2016
als biomarkers; amyotrophic lateral sclerosis Mark Garret is a neurologist and neuromuscular specialist focused on advancing clinical therapies for patients with amyotrophic lateral sclerosis (ALS). Since joining faculty at MGH, his research efforts have focused on the development and validation of biomarkers for ALS with a focus on defining presymptomatic disease stages of ALS. In conjunction with Dr. James Berry, he runs the Dominantly Inherited ALS Network (DIALS) / PREVENT ALS study, a large observational study of asymptomatic carriers for ALS disease causing genes. He leads multiple observational studies focused on biofluid and electrodaignostic biomarker development for ALS. He is also active as a clinical trialist focused on translating gene targeted therapies for familial ALS into clinical practice including work as site PI for the ATLAS trial of BIIB067 (tofersen) in SOD1 ALS gene carriers, the first trial of gene targeted therapy in pre-symptomatic ALS gene carriers.
Clinical Profile
mgarret@mgh.harvard.edu
Neurological Clinical Research Institute

165 Cambridge St
6th Floor
Boston, MA 02114