Peter Caravan, Ph.D.

Professor of Radiology
Harvard Medical School
Institute for Innovation in Imaging, Massachusetts General Hospital
Athinoula A. Martinos Center for Biomedical Imaging, Mass General Research Institute
Ph.D. University of British Columbia 1997
chronic liver disease; contrast media; coordination complexes; fibrin; fibrogenesis; fibroproliferation; fibrosis; gadolinium; inflammatory bowel disease; magnetic resonance imaging; manganese; organometallic compounds; pancreatic cancer; pet radiochemistry techniques; positron emission tomography; pulmonary fibrogenesis; renal fibrosis; serum albumin; thromboembolism; thrombosis

Peter Caravan, PhD, is co-director of the Institute for Innovation in Imaging (I3) at Massachusetts General Hospital and Professor of Radiology at Harvard Medical School. He leads a multidisciplinary and translational molecular imaging lab focused on the invention of novel molecular probes and their broad applications in cardiovascular, pulmonary, renal and hepatic diseases, as well as in cancers.  His research spans novel chemistry technologies from advanced MRI and PET imaging in animal models to applications in patient populations. He holds Investigational New Drug (IND) applications for a fibrin-targeted PET tracer and a collagen-targeted PET tracer that are currently being evaluated in over 10 clinical trials. He has invented molecular probes specific to fibrogenesis, acidosis, inflammation and thrombosis, as well as gadolinium-free MR contrast agents.

Dr. Caravan received a PhD in Inorganic Chemistry from the University of British Columbia. Following postdoctoral work at the EPFL (Switzerland), he spent 9 years at Epix Pharmaceuticals developing tissue-specific and responsive MRI contrast agents, one of which, gadofosveset, was approved by the FDA and the EMA. He co-invented EP-2104R, which was the first molecularly targeted MRI contrast agent to enter clinical trials, and RVP-001, a manganese-based general purpose MRI contrast agent currently in clinical development. Since joining MGH in 2007, he has been continuously funded by the NIH.

Caravan Lab Publications
Athinoula A. Martinos Center for Biomedical Imaging
CNY-Building #149
149 13th Street
Charlestown, MA 02129