Physician Investigator (Cl) Pediatrics, Mass General Research Institute

Professor of Pediatrics Harvard Medical School

Pediatrician Pediatric Infectious Disease, Massachusetts General Hospital

MD Duke University School of Medicine 1998

antibodies, bacterial; antigens, bacterial; bangladesh; cholera; cholera vaccines; fluid therapy; immunologic memory; vibrio cholerae; vibrio cholerae o1

Vibrio cholerae is the cause of cholera, a severe, rapidly dehydrating diarrheal illness. Much of the world’s population lives in areas without safe drinking water and is vulnerable to cholera. Cholera is endemic in many areas where it disproportionately affects children, and also occurs in large epidemics, such as the devastating epidemic that has followed the introduction of cholera into Haiti in 2010. Our research is focused on host-pathogen interactions and the innate and adaptive immune response to Vibrio cholerae, cholera vaccines, and in the area of susceptibility to cholera. We are invested in highly collaborative studies with a number of collaborators in the U.S. and in Bangladesh and Haiti where cholera is endemic.  The Harris & LaRocque laboratory is committed to training of investigators at all levels of experience, and to collaborations that enhance clinical and research capacity in areas where cholera and other enteric infections are endemic.