Lydia Lee Shook, MD


Clinicn Investigator, Asst Prf
Obstetrics & Gynecology, Mass General Research Institute
Assistant Professor of Obstetrics, Gynecology and Reproductive Biology
Obstetrics Gynecology & Repro. Bio. , Harvard Medical School
Associate Obstetrician & Gynecologist
Obstetrics & Gynecology, Massachusetts General Hospital
MD Yale University School of Medicine 2013
maternal-child health; maternal-fetal exchange; placenta

Dr. Shook is a Maternal-Fetal Medicine subspecialist and Assistant Professor in the Department of Obstetrics and Gynecology at Massachusetts General Hospital in Boston, Massachusetts, and an Investigator at the Vincent Center for Reproductive Biology.

The broad goal of Dr. Shook’s research is to better understand how prenatal exposure to acute and chronic maternal illnesses (COVID-19, diabetes, among others) impacts long-term offspring health outcomes.  Her work seeks to understand the role of the placenta in mediating the crosstalk between mother and fetus during pregnancy.  Together with Dr. Andrea Edlow, PI of the MGH Pregnancy Biorepository, she has made significant contributions to understanding the impact of COVID-19 infection and vaccines on maternal immunity and offspring health outcomes.  As the co-director of the Diabetes in Pregnancy Program with Dr. Camille Powe, Dr. Shook also engages in clinical research projects aimed at improving the care of pregnant individuals with diabetes and their newborns.

Dr. Shook is supported by the Transdisciplinary Harvard WRHR (Women’s Reproductive Health Research) Career Development Award for Gynecologists and Obstetricians (NIH/NICHD K12, 2021-2026), the Boston Area Diabetes Endocrinology Research Center (BADERC) Pilot & Feasibility Award (2024), the MGH Claflin Distinguished Scholar Award (2024-2025), and the Massachusetts Life Sciences Center Women’s Health Initiative First Look Award (2024).