Guoping Li, Ph.D.
Investigator, Instructor (M) Anesthesia, Critical Care and Pain Medicine, Mass General Research Institute |
Research Specialist Transplant Surgery, Massachusetts General Hospital |
Instructor in Medicine Harvard Medical School |
Research Interests
Research Narrative
I am interested in developing novel therapeutics by leveraging novel RNA species and extracellular vesicles, for treating cardiac, metabolic, and neurological diseases. My laboratory currently focuses on:
1. Cellular and extracellular tRNA-derived small RNAs (tDRs) in cardiac, metabolic, and neurodegenerative diseases;
2. Extracellular vesicles and non-vesicular nanoparticles-mediated intercellular and interorgan crosstalk in cardiac, metabolic, and neurodegenerative diseases.