Guoping Li, Ph.D.


Investigator, Instructor (M)
Anesthesia, Critical Care and Pain Medicine, Mass General Research Institute
Research Specialist
Transplant Surgery, Massachusetts General Hospital
Instructor in Medicine
Harvard Medical School
extracellular vesicles; heart failure; ipsc-based disease modeling; neurodegenerative diseases; trna-derived small rnas (tdrs)

I am interested in developing novel therapeutics by leveraging novel RNA species and extracellular vesicles, for treating cardiac, metabolic, and neurological diseases. My laboratory currently focuses on:
1. Cellular and extracellular tRNA-derived small RNAs (tDRs) in cardiac, metabolic, and neurodegenerative diseases;
2. Extracellular vesicles and non-vesicular nanoparticles-mediated intercellular and interorgan crosstalk in cardiac, metabolic, and neurodegenerative diseases.