Guoping Li, Ph.D.


Investigator, Assistant Professor (M)
Anesthesia, Critical Care and Pain Medicine, Mass General Research Institute
Assistant Professor of Anaesthesia
Harvard Medical School
cardiovascular disease; extracellular vesicles; neurodegenerative diseases; non-coding rnas; rna modifications; trna-derived small rnas (tdrs)

I am interested in developing novel therapeutics by leveraging novel RNA species and extracellular vesicles, for treating cardiac, metabolic, and neurological diseases. My laboratory currently focuses on:
1. Cellular and extracellular tRNA-derived small RNAs (tDRs) in cardiac, metabolic, and neurodegenerative diseases;
2. Extracellular vesicles and non-vesicular nanoparticles-mediated intercellular and interorgan crosstalk in cardiac, metabolic, and neurodegenerative diseases.