Yulong Xu, Ph.D.


Instructor in Investigation
Athinoula A. Martinos Center for Biomedical Imaging, Mass General Research Institute
Instructor in Radiology
Harvard Medical School
brain aging; brain imaging; diagnostic radiology; drug design; drug development; medicinal chemistry; neurodegenerative disease; pet radiochemistry techniques; positron emission tomography
Our multidisciplinary team of scientists, with expertise in medicinal chemistry, biochemistry, and radiochemistry, is dedicated to developing and applying innovative tools for imaging molecules within the living human brain using Positron Emission Tomography (PET). As a non-invasive imaging technique, PET has gained widespread recognition for its exceptional value in Central Nervous System (CNS) drug discovery. This powerful method yields crucial quantitative biomarker data, such as target expression levels and target occupancy measurements, which are otherwise unattainable in clinical settings.

Collaborating with various groups, we investigate molecular changes in the living brain throughout the progression of disease to enhance our understanding of underlying disease mechanisms and to facilitate the development of innovative therapeutic strategies. Furthermore, our team is actively engaged in additional projects aimed at creating new methods and tools for imaging novel molecular targets. These advancements will bolster our ability to translate fundamental research findings into effective treatments for human illnesses.
Publications
yulong.xu@mgh.harvard.edu
(617) 932-9739
Radiology
CNY-Building #149
149 13th Street
Charlestown, MA 02129-2000