Associate Professor of Radiology Harvard Medical School

Investigator Athinoula A. Martinos Center for Biomedical Imaging, Mass General Research Institute

alzheimer's disease; amyloid beta; aptamers nucleotide; brain tumor imaging; chemical exchange saturation transfer; collagen targeted mri contrasting agents; electron spin resonance spectroscopy; energy transfer; glioma; liver cirrhosis experimental; liver fibrosis; magnetic resonance imaging; magnetics; microscopy fluorescence; mri reporter genes; multiphoton; oncolytic virotherapy; receptors vascular endothelial growth factor; rna probes; spin labels; stroke

The Farrar group’s research program is focused on the development of new Magnetic Resonance molecular imaging methods and contrast agents. The tools being developed in our lab are being applied to studies of a wide range of diseases, including Alzheimer’s disease, cancer, liver fibrosis, and stroke. Our recent molecular imaging efforts have been focused on the development of chemical exchange saturation transfer (CEST) MRI reporter genes for imaging oncolytic virotherapy, deep learning based CEST magnetic resonance fingerprinting (MRF) methods for rapid and quantitative CEST imaging of brain tumors and stroke, collagen targeted MRI contrast agents for imaging liver fibrosis, and RNA aptamer probes for imaging amyloid-β plaques.