Investigator Anesthesia, Critical Care and Pain Medicine, Mass General Research Institute

Assistant Professor of Anaesthesia Harvard Medical School

biomedical signal processing; cardiovascular function; circadian rhythms; cognitive aging; dementia; sleep Dr. Li is a biomedical engineer and computational physiologist with a cross-disciplinary background in biomedical signal processing, physiological measurement, sleep and circadian physiology, and neurophysiology research. Dr. Li directs the Laboratory for Sleep and Digital Health (LSDH) and serves as the Research Director of the Medical Biodynamics Center (MBC). While his primary focus is on research, Dr. Li is equally passionate about teaching and mentoring others—a pursuit he considers essential to his professional and personal growth. Dr. Li was honored to receive the 2022 Early Career Mentoring Award from the Department of Medicine at Brigham and Women’s Hospital. Additionally, Dr. Li is privileged to serve on the Editorial Board of the journal SLEEP and as an Assistant Editor for the Journal of the American Heart Association.

In LSDH, the research focuses on identifying individuals at elevated risk of cognitive impairment, Alzheimer’s disease, and related dementias by utilizing novel digital biomarkers linked to sleep and circadian rhythms. The LSDH also investigates the role of sleep and circadian regulation in cognitive function and resilience across diverse populations, with a special emphasis on vulnerable and underrepresented groups. To support individualized, proactive management of sleep and circadian health, the LSDH is also dedicated to developing innovative, cost-effective, and non-invasive contactless monitoring solutions including cutting-edge products and algorithms.