Mehdi Jorfi, Ph.D.

Assistant Professor of Neurology
Harvard Medical School
Assistant Investigator
Neurology, Mass General Research Institute
Affiliated Faculty
Center for Engineering in Medicine, Massachusetts General Hospital
alzheimer's disease; bioengineering; induced pluripotent stem cells; microfluidics; multiple sclerosis; neurodegeneration; neuroimmunology; neuroscience

Dr. Jorfi is an Assistant Professor of Neurology at Harvard Medical School and Mass General Hospital. He obtained his Ph.D. from the University of Fribourg in 2014. He then completed his postdoctoral work at Massachusetts Institute of Technology (MIT) and Mass General Hospital. As a postdoc and later an instructor at Mass General Hospital, Dr. Jorfi studied neuroimmune interactions in Alzheimer’s disease. He is currently a faculty member at the Genetics and Aging Research Unit, where his work focuses on the interplay between peripheral immune cells and neurodegeneration. His lab employs multicellular engineered living systems as human surrogates to model components of the human immune system and gain insights into the neuroimmune mechanisms in neurological diseases, particularly Alzheimer’s disease and multiple sclerosis. His research aims to elucidate important signaling between brain cells and the immune system and how these are perturbed in chronic neurological diseases. Dr. Jorfi is the recipient of several grants, including NIH R01 grants and Cure Alzheimer’s Fund, as well as multiple awards, such as the honorary Faculty Science Prize

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