Nabeel M. Bardeesy, Ph.D.

Associate Investigator
Cancer Center, Mass General Research Institute
Associate Investigator
Center for Cancer Research, Massachusetts General Hospital
Associate Professor of Medicine
Harvard Medical School
Affiliate Faculty
Harvard Stem Cell Institute
carcinoma, pancreatic ductal; cyclin-dependent kinase inhibitor p16; genes, ras; pancreatic neoplasms; protein-serine-threonine kinases; tumor suppressor protein p14arf Pancreatic cancer and biliary cancer are among the most lethal types of human cancers. The Bardeesy laboratory has developed a series of genetically engineered mouse models to define the role of key gene mutations in driving these cancer types. Current projects focus on defining roles for cancer genes in controlling the way cells modulate their growth and utilize energy in response to available nutrients, and on identifying epigenetic regulators responsible for changes in cellular differentiation state that lead to cancer initiation and maintenance.
Bardeesy Lab Publications

Simches Building
185 Cambridge Street
Boston, MA 02114