Daniel Pratt, M.D.


Physician Investigator (Cl)
Gastroenterology, Mass General Research Institute
Assistant Professor of Medicine
Harvard Medical School
Assistant Physician
Gastroenterology, Massachusetts General Hospital
MD Johns Hopkins University School of Medicine 1989
bile acids and salts; bile ducts intrahepatic; cholangiocarcinoma; cholangitis; cholestasis; hepatitis autoimmune; hepatocellular carcinoma; igg4 associated liver disease; liver diseases; primary biliary cholangitis; primary sclerosing cholangitis; ursodeoxycholic acid; viral hepatitis

Daniel S. Pratt, MD is an Assistant Professor of Medicine at Harvard Medical School, Clinical Director of Liver Transplantation, and Director of the Autoimmune and Cholestatic Liver Center at the Massachusetts General Hospital.

Dr. Pratt received his B.A. from Bowdoin College and his M.D. from the Johns Hopkins University School of Medicine.  He completed a residency in Internal Medicine and a fellowship in Gastroenterology and Hepatology at the Tufts-New England Medical Center. He served on the faculty of the Tufts University School of Medicine from 1995 until 2004.

Dr. Pratt was the Medical Director of the Liver Transplant Program and Clinical Chief of the Division of Gastroenterology at the Tufts Medical Center. He joined the faculty of the Harvard Medical School and the MGH Gastrointestinal Unit in 2004.

Dr. Pratt's particular area of clinical interest is autoimmune and cholestatic liver disease including autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, and IgG4 associated liver disease.He also does work in cholangiocarcinoma, hepatocellular carcinoma, viral hepatitis, and cirrhosis/endstage liver disease. Dr. Pratt is the head of the PSC Registry at MGH.

Dr. Pratt has written extensively on liver disease and has been the recipient of numerous teaching awards.