Academic Dean for Partners Healthcare System Harvard Medical School

Professor of Medicine Harvard Medical School

Associate Physician Nephrology, Massachusetts General Hospital

MD University of Pennsylvania School of Medicine 1991

MPH Harvard School of Public Health 1997

ergocalciferols; gestational diabetes; kidney failure chronic; pre-eclampsia; pregnancy trimester first; renal dialysis; vitamin d; vitamin d deficiency ... Dr. Thadhani and his collaborators have developed novel diagnostic tests for preeclampsia, and are now arduously working on therapies to safely prolong pregnancy in women with very severe preterm preeclampsia. He is actively performing first-in-human randomized trials based on extensive pilot studies (Circulation 2011 and the Journal of the American Society of Nephrology 2015). His pregnancy studies center on human research supporting recent findings emerging from basic science collaborations in the area of angiogenic factors and preeclampsia. He has performed pilot and proof-of-concept studies, retrospective and prospective (>10,000 women, > 30,000 blood samples) studies, and planned and performed interventional trials. A diagnostic test his team developed is currently in the clinic in Europe. With regard to vitamin D, his team has performed several hypothesis-generating observational studies suggesting that therapy with activated vitamin D sterols is associated with improved survival among patients with renal failure. These series of observational studies have included thousands of dialysis patients throughout the U.S. ...