Investigator, Assoc Prof (M) Molecular Pathology Unit, Mass General Research Institute

Associate Professor of Pathology Harvard Medical School

MGH Research Scholar 2024-2029 Mass General Research Institute, Massachusetts General Hospital

artificial intelligence; crispr; crispresso; epigenetics; epigenomics; genetically influenced cancer; genome editing; genomics; single-cell analysis; stream

The focus of the Pinello laboratory is to use innovative computational approaches and cutting-edge experimental assays such as genome editing and single cell sequencing to systematically analyze sources of genetic and epigenetic variation and gene expression variability in human traits and diseases.

The lab uses machine learning, data mining and high performance computing technologies, for instance parallel computing and the new cloud oriented architectures, to solve computationally challenging and Big Data problems associated with next generation sequencing data analysis.

Our mission is to use computational strategies to further our understanding of disease etiology and to provide a foundation for the development of new drugs and more targeted treatments.