Physician Investigator (NonCl)
Surgical Oncology,
Mass General Research Institute
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Professor in Residence of Orthopedic Surgery
Harvard Medical School
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Professor in Residence of Surgery
Harvard Medical School
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Research Staff
Surgical Oncology,
Massachusetts General Hospital
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Research Staff
Orthopaedic Surgery,
Massachusetts General Hospital
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| MD University of Milan-Medical School 1964 |
antibodies anti-idiotypic; antigens neoplasm; breast cancer; histocompatibility antigens class i; hla antigens; melanoma; monoclonal antibodies; pancreatic ductal adenocarcinoma; triple-negative breast cancer
I am interested in characterizing the molecular basis and the clinical significance of HLA antigen defects in malignant cells. In addition I am interested in developing novel tumor antigen-specific monoclonal antibody based strategies which target both cancer initiating cells and differentiated cancer cells. I am using melanoma, pancreatic ductal adenocarcinoma and triple negative breast cancer.
