David Nathan, M.D.

Clinical Research Center, Massachusetts General Hospital
Diabetes Center, Massachusetts General Hospital
Physician Investigator (Cl)
Diabetes, Mass General Research Institute
Professor of Medicine
Harvard Medical School
MD 1975
blood glucose; brain insulin resistance; clinical research; diabetes; diabetes mellitus type 1; diabetes mellitus type 2; diabetic retinopathy; glycemic index; hemoglobin a glycosylated; hypoglycemic agents

David M. Nathan, MD, is the Mass General CRC Program Director, a role he assumed in 1991. Dr. Nathan is a Physician in the Department of Medicine, Professor of Medicine at Harvard Medical School, an active clinical investigator in the Diabetes Unit and an active investigator on the CRC since 1980.

He is also the Director of the Mass General Diabetes Center, which includes the Diabetes Clinic and Diabetes Research Center. Dr. Nathan's clinical research, which investigates novel means of controlling glycemia in the physiologic range in both Type 1 and Type 2 diabetes and the short and long-term effects of such therapy on diabetic complications, has earned him an international reputation as an outstanding clinical investigator.

Much of his clinical research over the past 20 years, including his national leadership of NIH-sponsored studies such as the Diabetes Control and Complications Trial (DCCT), the Epidemiology of Diabetes Interventions and Complications (EDIC) study, and the Diabetes Prevention Program (DPP), has been performed on the CRC. Dr. Nathan oversees all aspects of the CRC operations.